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Biosystems A (IGA) immunoglobulin reagent

04 Haziran 2017
4 kez görüntülendi
Biosystems A (IGA) immunoglobulin reagent

Biosystems A (IGA) immunoglobulin reagent

Reagents for the measurement of immunoglobulin A (IgA) concentration in human serum or plasma.

The obtained values are useful as an aid in the evaluation of the humoral immunity and for diagnosis and control of multiple myeloma.

This reagent is for use in the BioSystems BA analyzers or in other analyzer with similar performance characteristics.

 

CLINICAL SIGNIFICANCE
Approximately 10 to 15% of serum immunoglobulin is IgA. In its monomeric form, its structure is
similar to that of IgG, but 10 to 15% of IgA in serum is dimeric.

Plasma IgA concentration is decreased in inherited or acquired deficiencies of immunoglobulin
production1,2

 

Biosystems A (IGA) immunoglobulin reagent PRINCIPLE OF THE METHOD

Immunoglobulin A in the sample precipitates in the presence of anti-human immunoglobulin A
antibodies.

The light scattering of the antigen-antibody complexes is proportional to the immunoglobulin A concentration and can be measured by turbidimetry3,4

CONTENTS AND COMPOSITION

A. Reagent: 1 x 60 mL. Imidazole buffer 0.05 mol/L, sodium azide 0.95 g/L, pH 7.5.
B. Reagent: 1 x 15 mL. Goat anti-human IgA antibodies, sodium azide 0.95 g/L.

STORAGE AND STABILITY

Store at 2-8ºC.
Components are stable once opened until the expiry date marked in the label if they are stored
well closed and care is taken to prevent contamination during their use.

 

Brand: Biosystems

Biosystems A (IGA) immunoglobulin reagent

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